Jiřì Liška, Konrad Siala, Václav Hole D;ek, Štěpánka Sobotová and František Šefrna
Mulačova Hospital, Faculty Hospital, Plzeň, Czech Republic
From 1998-2012 we examined 3912 samples of umbilical blood taken from children born into families with a positive history of allergy in one or both parents. The results revealed that allergy is strongly linked with family history (p≤0.0001). We also detected differences in seasonality, especially with regards to pollen allergies. High values of umbilical IgE, together with a positive family history of allergy an indication for inclusion of patients into the treated group, which, during the years of 2011-2015 where treated with Colinfant Newborn (a lyophylized non-pathogenic strain of E.coli). Normalisation of IgE was seen in 90% of patients with previously increased levels. IgG and IgA at the first and the third year of life were also normalized (p≤0.0001). This also corresponded with an entirely negligible subsequent morbidity of the monitored group of children (up to 4 years of life) when compared with the control group.