Pejakov L.J., and Cejovic V.
Clinical Center of Montenegro, Podgorica, Montenegro, Yugoslavia
Background: Nowadays we are witness of ceaseless overgrow of multidrug and pan drug resistant Gram negative bacteria in hospital settings . Colistin, cationic polypeptide antibiotic discovered in 1947, has been found to be the only efficient against these pathogens.
Aim: To analyze series of patients to whom colistin has been prescribed over three month period and possible causes of development of Acinetobacter species resistant to all other classes of available antibiotics.
Setting: Tertiary level mixed type 16-bed intensive care unit (surgical/medical) at Clinical Center of Montenegro.
Method: Observational prospective/ retrospective analysis of medical documentation.
Results: There were eight patients to whom colistin has been prescribed. Their average age was 48.6 years, length of hospitalization 38 days, APACHE II score 28. and 34 days of mechanical ventilation. Initial antibiotic therapy were cephalosporins third generation, aminoglicozide and metronidazole.
Conclusion: Irrational initial antibiotic therapy might be blamed for Acinetobacter sp strains and the use of colistin.
 Mijovic G; Pejakov L; Vujosevic D. Antibiotic susceptibility of Acinetobacter species in intensive care unit in Montenegro. DOI: http://dx.doi.org/10.1179/1973947815Y.0000000037