| Scientific Contributions:
While working in NIEHS/NIH, she is the one who, for the first
time, isolated and purified cytochrome P450 in a biocatalytically
active form from an extrahepatic tissue, a lung (Arinç,
E. & Philpot, R.M., J. of Biol. Chem., 25, 3213-3220,
1976), which opened up a road for understanding of CYP induced
chemical carcinogenesis in lung and other extrahepatic tissues.
Her scientific contributions are over 150 publications including
articles, proceedings and book chapters.
Professional Experience: She has been on
the faculty in the department of Biological Sciences at the
Middle East Technical University , Ankara, Turkey since 1976
and since 1988 has been professor of Biochemistry and Molecular
Biology. She was on sabbatical leave as a Fulbright Scholar
in the department of Biochemistry, University of Connecticut
Health Center, Connecticut (1985-1987). Dr. Arinç was
the head of the department of Biological Sciences (1984-1985)
and of the Joint Graduate Program in Biochemistry in (1982-1985)
and in (1987-1998).
Research Interests: Cancer pharmacogenetics,
toxicogenomics, chemical carcinogenesis, nutrition and cancer
prevention, cytochrome P450 dependent drug metabolism in disease
state, i.e in diabetics; The structure, function and, the
regulation of the hepatic and pulmonary cytochrome P450 dependent
drug metabolizing enzymes. In vivo and in vitro
drug-drug, drug-toxicant interactions; Biotechnology, biomarkers
and pollution monitoring.
Professional Societies and Activities: Member
of the Editorial board of Journal of Biochemical and Molecular
Toxicology (1991-). Eczacibasi Foundation Scientific Award
in Medicine (1984). Member of Turkish Academy of Sciences
(1996-). Organizer and Director of the NATO Advanced Study
Institute on “Molecular Aspects of Monooxygenases and
Bioactivation of Toxic Compounds in Izmir, Turkey 1989. Director
of the NATO Advanced Study Institute on “Molecular Aspects
of Oxidative Drug Metabolizing Enzymes and Their Significance
in Environmental Toxicology, Chemical Carcinogenesis and Health”
in Kusadasi, Turkey, 1993. Organizer and Director of the NATO
Advanced Study Institute on “Molecular and Applied Aspects
of Oxidative Drug Metabolizing Enzymes”. Antalya, Turkey,
1997, and co-editor of the above NATO ASI Proceedings.
Co-chair of 19th European Workshop on Drug
Metabolism held in Antalya, Turkey, in 2004.
Chair of the 9th International ISSX (International
Society for Study of Xenobiotics) Meeting to be held in Istanbul
on September 4-8, 2010.
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