Poster Presenter

Effectiveness of Praziquantel in Treatment of Intestinal Amoebiasis and Giardiasis
K.A.Mohammad, S.K.Strak, A.M.Jawad, I.O.Al-Sadoon, Nadham Kadham Mahdi Al-Adday.


This is a randomized clinical trial to compare the efficacy of praziquantel with that of metronidazole in amoebiasis and giardiasis. A total of 111 adult out-patients, shown clinically and by stool examination to have E.histolytica (n=90)or G.lamblia (n=21) infections, were treated with praziquantel 40mg/kg B.W, or with metronidazole, 800mg 3 times a day for 5 days for amoebiasis and 400mg 3 times a day for 7 days for giardiasis. It was observed that the disappearance of clinical symptoms after treatment with praziquantel was remarkably. It was also useful in eliminating cysts of E.histolytica where metronidazole is known to be ineffective. A good clinical and laboratory response was obtained in patients with giardiasis at a rate of 70% and 78% in the praziquantel and metronidazole groups respectively.