Poster Presenter

Utilization Of Some Flavonoid Compounds In Cancer Chemoprevention And Treatment
Miadokova, E., Nadova, S., Cipak, L., Galova, E., Sevcovicova, A., Kopaskova, M., Hudecova, A., Hasplova, K.
Slovakia

New drugs to prevent and/or fight cancer are still a challenge of great importance. Nature is a ponderable source for various medicaments. Results of many scientific efforts have shown that many representatives of one vast and variable group of natural compounds known as flavonoids may stand in a queue for being the chemopreventive and chemotherapeutic drugs of future. Research in our laboratory also showed potential beneficial effects of some flavonoid substances, namely isorhamnetin, myricetin and kaempferol. They were studied in vitro for their antioxidant/anticarcinogenic properties, which are important for cancer chemoprevention and treatment. Their prosperous effects on chemotherapy-induced apoptosis were also investigated using leukemia cells. Results obtained indicated their potential usefulness in oncology. Our work was supported by the grants: VEGA 1/0008/08, 2/0072/09, SK-BG-0017-08.