The 2nd International Conference on Drug Discovery & Therapy: Dubai, February 1 - 4, 2010


Poster Presenter

The survey of Influence Of Lactic Acid Bacteria On Decrease Of Cholesterol And Entrotoxigenic Bacteria Colonization

Sedigheh Mehrabian, Mahsa Dameshghian
Iran

Lactobacillus is a human normal flora. These bacteria suppressed the colonization of pathogenic bacteria in gastrointestinal tract.
Four pure strain of lactobacillus:L. acidophillus, L. casei, L. jonssoni, L. plantarum and four genus of entrotoxigenic bacteria: Bacillus cereus, Staphylococcus aureus, Salmonella typhimorium and E.coli were used in this study. entrotoxigenic bacteria decreases were analyzed by two layer culture, well procedure, disk diffusion and turbidimetery methods.

In two layer culture method, plates with L. acidophilus, sever decreased S. aureus, moderate decreased of B. cereus, S.typhimorium and E.coli colony number. Plates with L. plantarum, mild decreased all of entrotoxigenic bacteria colony number. In well diffusion, nutral and acidic extracted of lactobacillus suppressed the growth of S. aureus but not effect on E.coli.

Also cholesterol assimilation determined by difference in cholesterol content in the medium before and after the incubation period, showed that all Lactobacilli strains were able to assimilate cholesterol at varing levels ranging from 36 to 74 μg/ml.




















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