The 2nd International Conference on Drug Discovery & Therapy: Dubai, February 1 - 4, 2010

Poster Presenter

Prostate Cancer, Studies on Aetiological, Therapeutic, Prognostic and Prophylactic Factors
Thomas Tallberg and Faik Atrochi

Cancer of the prostate gland (CaP) is a hormone dependent disease lacking non-invasive curative treatments and a comprehensible aetiology. Signs for adrenal involvement coupled with metabolic factors led to this study on the aetiology of CAP. Two different neuroendocrine components produced by adrenal zona reticularis cells (ZR) were found to be involved. One increases serum FSH, the other prolactin (PRL) levels. This curative ZR feed-back reaction can be activated in CaP patients by dietary supplementation utilizing ready-made powders (for 3€/day) containing all missing natural metabolic factors thus compensating the aetiological metabolic deficiency. Components prescribed are; amino-acids serine (Ser), arginine (Arg) plus trace-element ions; strontium (Sr), vanadium (V), and molybdenium (Mo) and vital central nervous system CNS-lipids, (Neurofood Ltd. Helsinki). Efforts to correct etiological metabolic deficiencies may prevent recurrent cancers. This biological treatment can arrest CaP progression, cure bone and soft tissue metastases. Ingested Serine causes substrate inhibition of PSA (a serine protease). There is a new incentive for screening since CaP can primarily be treated by dietary supplementation. Good prognosis show increased FSH, prolactin (PRL) and SHBG levels, while DHEAS and PSA decline. With PSA exceeding 15ng/mL, intermittent total androgen ablation therapy [Zoladex 3.6g + Androcur® for only 10 days] is prescribed, in synergy with our CaP powders to avoid a hormone refractory state. Watchful waiting is not acceptable, since no effort is made to stop CaP progression.
















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