Poster Presenter

MK615, an Extract of the Japanese Apricot (Ume), is a Promising Anti-Cancer And Anti-Inflammatory Compound
Aya Nakagawa, Toshihiko Sawada, Toshie Okada, Shozo Mori, Tatsushi Ohsawa, Masakazu Adachi, Keiichi Kubota
Japan

A variety of Japanese apricot, PrunusmumeSieb.etZucc, known in Japan as ume, has been believed to be a rich source of healthy substances. MK615 is an extract derived from ume and contains several triterpenoids and other unknown substances. Accumulating evidence indicates that MK615 exerts an anti-cancer effect by inducing apoptosis and autophagy, and suppressing Aurora kinases A and B and accumulate cells in G2-phase of cell-cycle. Also, MK615 also exerts an anti-inflammatory effect.

Ume is a rich source of anti-cancer and anti-inflammatory substances. MK615 may therefore be a promising new avenue for the treatment of cancer and inflammation.