Poster Presenter

Biologics of Organo-Metallic Complexes Affecting Drugs Shown by Uv-Visible Spectrophotometry
Al-Taiar, A.H. and Bentayeb K.
Algeria

Studies of complexes of Ni, Cr, Fe and Cu salts with aminoacids on drugs using UV-Visible spectrophotometry.

Aminoacids forming essential parts of human body represent a very interesting class of compounds because of their utility in:

a normal metabolic processes involving all living organisms and,

b Protection of the organism from toxic effects of these metals.

The importance of these aminoacids is due to their ability to form stable complexes with various metallic cations by chelation reactions.

In this study, UV-visible absorption studies of these complexation reactions accured between some aminoacids as electron donors and Ni, Cr, Fe and Cu salts as electron acceptors are studied. From these reactions some paramters such as, reaction equilibrium constant, k, molar extinction coefficient, absorption bands energy, E, for the produced organo-metallic compounds,the ionization potential of the electron donor, I and the reactions Gibbs free energy changes, G were calculated and discussed for the above reactions.

Besides, kinetic studies were done for these complexation reactions.

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