Session Speaker
Radioisotope Induced X-ray
Fluorescence – A Diagnostic Tool for Drug Analysis and its Effect
on Human Health and Diseases
Daisy Joseph
Energy dispersive X-ray Fluorescence (EDXRF)
– an ideal technique for detecting trace elements in drugs have
been used for analyzing drugs containing Zn supplements used for growth
in children and ayurvedic medicines containing toxic elements such
as Arsenic(As) and Mercury.Hg) Zn supplements (Jasad Bhasm) manufactured
by various manufacturers were analyzed for their trace elements besides
Zn and were compared with laboratory preparations. Similarly the ayurvedic
medicines from different companies were analyzed for their metal composition.
All samples in powder form were pelletized and analyzed using an X-ray
spectrometer consisting of a Cd 109 radioisotope source, Si(Li) detector
of resolution 170 eV at 5.9 KeV Mn X-ray ,premaplier,amplifier and
a PC based Multichannel analyzer Varying amounts of trace elements
were detected in Jasad Bhasm and interesting results (As and Hg) were
seen in the ayurvedic medicines in addition to other trace elements
such as K,Ca,Fe,Cu and Zn Their levels of toxicity and significance
to human health and diseases will be discussed in the following sections
of the paper.
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