The 2nd International Conference on Drug Discovery & Therapy: Dubai, February 1 - 4, 2010


Session Speaker

Stimulated whole saliva composition in dental healthy students and menopausal woman
Farzaneh Agha-Hosseini

Background & Aim: Advantages of easy access and non-invasive collection have caused saliva to be a unique fluid as a diagnostic medium during recent years. By the other hand, one of the most complaints of menopausal women is xerostomia. This study determined and compared the stimulated whole saliva biochemical parameters in female healthy dental students of Tehran University of Medical Sciences living in the students’ dormitory and healthy menopausal women.

Methods & Materials: In a cross sectional study, five ml stimulated whole saliva samples were obtained by expectoration of 20 girl students (mean age 22 years) and 20 menopausal women (mean age 56.8 years). Sodium concentration measured by Flame-photometry method and the other saliva composition were measured by spectrophotometer and affiliated kits as follow: total protein by the Biuret method, phosphorus by ammonium molybdate and stannous chloride complex, ca++ by Arsenazo reaction and magnesium by the xylidyl blue complex methods. The data was analysed for mean, standard deviation and standard error mean using SPSS program. Students’s unpaired t-test was used for comparison of stimulated saliva compositions between the two groups.

Results: Stimulated whole saliva concentrations of total protein, magnesium, calcium and sodium were respectively in students and in menopausal women.

Conclusion: there were no significant differences in the stimulated whole saliva sodium and calcium in the two groups, while stimulated whole saliva magnesium levels in students and total protein in menopausal women were significantly higher.















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