The 2nd International Conference on Drug Discovery & Therapy: Dubai, February 1 - 4, 2010


Session Speaker

Emergence of Multi Drug Resistant Strains of s Isolated from Urinary Tract Infection
Shohreh Farshad, Reza Ranjbar and Mojtaba Anvarinejad
Iran

Introduction and Objectives: A current phenomenon of great concern in the medical community in developing countries is raising multi-drug resistant organisms, and their problems with curing the infections in children. In this study, we evaluated the multi drug resistant strains of Escherichia coli isolated from urinary tract infection in children in Southern Iran.

Materials and Methods: Totally 90 strains of E. coli were collected from urine samples of children, aged from 1 month to 14 years, referred to Motahary Hospital of Jahrom. After confirmation of urine culture which is expressive of urinary infection, gram stain and biochemical differential test was done for the isolates and then susceptibility of all of them to different antibiotics was determined by standard disk diffusion method.

Results: The antibiogram patterns of isolates showed a high percentage of multi drug resistant phenotype among the E. coli strains. Seventy seven percent of the isolates were resistant to three or more antibiotics. The predominant pattern among these strains (14.4%) included resistance to ampicillin, co-trimoxazole and tetracycline which was repeated among 13 strains.

Conclusion: With regard to the present data and high percentage of multi drug resistant strains of E. coli, regular monitoring antimicrobial drug resistance in the different areas is necessary to prevent unsuitable utilization of drugs which is the most important cause of emerging multi drug resistant strains.

 












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