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The 3<sup>rd</sup> International Conference on Drug Discovery & Therapy: Dubai, February 7 - 11, 2011

Recent Advances in Spectroscopy (Track)

Determination of pH In food, Drug and Environment By Flow Injection Analysis

A.Kazemzadeh
Materials & Energy Research center P.O.Box 14155 - 4777 Tehran - IRAN

Abstract:

A pH Chemical sensor with high sensitivity is achieved by direct attachment of Cong Red indicator over a Sol-Gel and polymeric film. This sensor is prepared by attaching Congo red over polymeric film or by adding indicator in tetra metoxysilan (TMOS) in order to determining hydrogen ion in food, environment and drug solution with high concentration of hydrogen and producing strong signals and rapid response time.

Congo red is used over a Sol-Gel or polymeric film as a chemical-optical sensor. Sol-Gel layer and polymeric membrane have long lifetime as (>15 months) and (>12 months) and short response time as (>6 sec) and (>9 sec) respectively. It is a simple method and applied dye has low price and highly used.

In this paper, the purpose is investigation and optimizing condition for measurement of pH in solution by flow injection analysis. Sol-Gel layer and polymeric film. Finally morphology of polymeric film and Sol-Gel layer surfaces were investigated by AFM apparatus and subsequently Sol-Gel layer have been found to be a favorite base for chemical sensor a fabrication..

Keywords: Optical, pH, Congo Red and Food, Drug Sensing Film.